What Does QUININE Mean in NYT Spelling Bee?

QUININE is a bitter substance obtained from cinchona bark.

It appears in the accepted-answer list for the September 22, 2026 NYT Spelling Bee.

For U.S. English, Cambridge gives the pronunciation approximately as KWY-nine.

It is spelled Q – U – I – N – I – N – E.

NYT Spelling Bee
More things surfaced by NYT Spelling Bee
01

Quick answer

Word QUININE

Spelling Q – U – I – N – I – N – E

U.S. pronunciation KWY-nine

Spelling Bee status Accepted on September 22, 2026

Pangram No

02

What does QUININE mean?

QUININE is the name of a bitter substance derived from cinchona bark.

The word has medical and historical uses, but this page only explains the vocabulary needed to understand the puzzle answer.

It is not a treatment or medication guide.

03

How do you spell QUININE?

The spelling is:

Q – U – I – N – I – N – E

Two details make it easy to mistype:

I appears twice.

N appears twice.

The ending is:

-I-N-E

not:

-I-N

04

How do you pronounce QUININE?

Cambridge gives the U.S. pronunciation:

/ˈkwaɪ.naɪn/

A simple approximation is:

KWY-nine

The U.K. pronunciation is different, so U.S. readers may hear another valid pronunciation in British sources.

05

Why is QUININE accepted in Spelling Bee?

The September 22, 2026 puzzle uses N as the required center letter with O, Q, U, X, E and I available around it.

QUININE uses only available letters and contains N.

The official answer list includes it.

06

Is QUININE the pangram?

No.

A pangram must use every letter in the puzzle.

QUININE does not use O or X.

The September 22 pangram is EQUINOX.

07

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Evidence

Sources

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